Gianluca Sbardella Selected Research

2- (sec- butylthio)- 6- (1- (2,6- difluorophenyl)propyl)- 5- methylpyrimidin- 4(3H)- one

1/2020	Reverse transcriptase inhibitors promote the remodelling of nuclear architecture and induce autophagy in prostate cancer cells.
1/2020	Reverse transcriptase inhibition potentiates target therapy in BRAF-mutant melanomas: effects on cell proliferation, apoptosis, DNA-damage, ROS induction and mitochondrial membrane depolarization.
8/2011	Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors.

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Gianluca Sbardella Research Topics

Disease

11	Neoplasms (Cancer) 07/2022 - 11/2005
4	Leukemia 03/2015 - 11/2006
3	Melanoma (Melanoma, Malignant) 01/2020 - 10/2006
2	Acquired Immunodeficiency Syndrome (AIDS) 01/2020 - 02/2004
2	Genomic Instability 01/2020 - 06/2014
1	Nervous System Diseases (Neurological Disorders) 04/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Carcinogenesis 01/2020
1	Prostatic Neoplasms (Prostate Cancer) 01/2020
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2017
1	Medulloblastoma 01/2017
1	Neoplasm Metastasis (Metastasis) 01/2017
1	Colonic Neoplasms (Colon Cancer) 01/2017
1	Colorectal Neoplasms (Colorectal Cancer) 01/2017
1	Pathologic Processes 01/2015
1	Glioblastoma (Glioblastoma Multiforme) 03/2014
1	Wounds and Injuries (Trauma) 09/2013
1	Breast Neoplasms (Breast Cancer) 05/2013
1	Coronary Artery Disease (Coronary Atherosclerosis) 10/2012
1	Carcinoma (Carcinomatosis) 11/2011
1	Cardiomyopathies (Cardiomyopathy) 02/2011
1	Myeloid Leukemia (Leukemia, Myelocytic) 04/2008

Drug/Important Bio-Agent (IBA)

5	Histone Acetyltransferases (Histone Acetyltransferase)IBA 01/2022 - 02/2011
4	Proteins (Proteins, Gene)FDA Link 04/2022 - 09/2013
4	Histones (Histone)IBA 01/2022 - 11/2006
4	NucleosidesIBA 01/2020 - 04/2008
4	Lysine (L-Lysine)FDA Link 03/2015 - 02/2011
3	Reverse Transcriptase InhibitorsIBA 01/2020 - 08/2011
3	2- (sec- butylthio)- 6- (1- (2,6- difluorophenyl)propyl)- 5- methylpyrimidin- 4(3H)- oneIBA 01/2020 - 08/2011
3	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2020 - 08/2011
3	coactivator-associated arginine methyltransferase 1IBA 01/2017 - 07/2011
2	efavirenz (Sustiva)FDA Link 01/2020 - 02/2004
2	Human immunodeficiency virus 1 reverse transcriptaseIBA 08/2011 - 10/2006
1	Histone DemethylasesIBA 07/2022
1	DNA Transposable Elements (Element, IS)IBA 01/2020
1	Proto-Oncogene Proteins B-rafIBA 01/2020
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2020
1	Retroelements (Retrotransposon)IBA 01/2020
1	Cadherins (E-Cadherin)IBA 02/2019
1	Ether (Diethyl Ether)IBA 02/2019
1	Phospholipids (Phosphatides)FDA LinkGeneric 02/2019
1	LipidsIBA 02/2019
1	Phosphates (Orthophosphate)IBA 02/2019
1	Pharmaceutical PreparationsIBA 05/2018
1	EndocannabinoidsIBA 01/2017
1	RimonabantIBA 01/2017
1	CateninsIBA 01/2017
1	DNA (Deoxyribonucleic Acid)IBA 06/2014
1	LigandsIBA 03/2014
1	4-phenylquinazoline-2-carboxamidesIBA 03/2014
1	quinolineIBA 03/2014
1	pentadecylidenemalonate 1bIBA 09/2013
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2013
1	TubulinIBA 09/2013
1	SirtuinsIBA 09/2013
1	Histone Deacetylase InhibitorsIBA 09/2013
1	Estrogen ReceptorsIBA 05/2013
1	Nitroglycerin (Dynamite)FDA LinkGeneric 10/2012
1	Hormones (Hormone)IBA 07/2011
1	Connexin 43 (Connexin43)IBA 02/2011
1	AcetylesteraseIBA 02/2011
1	CurcuminIBA 04/2008
1	Eosine Yellowish-(YS) (Eosin)IBA 04/2008
1	sirtinolIBA 04/2008
1	TriazinesIBA 10/2006

Therapy/Procedure

5	Therapeutics 01/2020 - 02/2004